Comparative Evaluation of 24-Hour Thyroid 131I Uptake Between g Camera–Based Method Using Medium-Energy Collimator and Standard Uptake Probe–Based Method

نویسندگان

  • Biju K. Menon
  • Ramesh D. Rao
  • Amit Abhyankar
  • M. G. Ramakrishna Rajan
  • Sandip Basu
چکیده

The objective of the study was to make a quantitative comparison of 24-h thyroid uptake calculated by γ camera–based and thyroid uptake probe–based methods after administration of a diagnostic 131I capsule in patients with benign thyroid disorders. Methods: The study group comprised 66 patients, of whom 26 were male (28–67 y old) and 40 female (20–65 y old). These patients had benign thyroid disorders (primarily hyperthyroidism [thyrotoxicosis]), most of whom had been referred for evaluation before radioiodine treatment. 131I (25 μCi [925 MBq]) was administered, and 24-h thyroid uptake was calculated using a probe-based method and a camera-based method with a medium-energy parallel-hole collimator. The paired t test was used to check the variation in values obtained by these 2 methodologies. Result: Of the 66 patients included in this study, 45 had clinical thyrotoxicosis and 21 had nonthyrotoxic multinodular goiter. In the group with thyrotoxicosis, neck uptake ranged from 40.13% to 97.1% by the probe-based method and 36.89% to 95.9% by the camera-based method. In the group with clinically nonthyrotoxic goiter, neck uptake ranged from 1.4% to 38.4% by the probe-based method and 0.6% to 34.8% by the camera-based method. Paired t testing was performed on both groups of patients, and P values were less than 0.05, showing good agreement within the 2 groups of data. Conclusion: The camera-based method is a good substitute for the probe-based method; though not producing identical results, the former could be used to derive useful quantitative information on thyroid function.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparative evaluation of 24-hour thyroid 131I uptake between γ camera-based method using medium-energy collimator and standard uptake probe-based method.

UNLABELLED The objective of the study was to make a quantitative comparison of 24-h thyroid uptake calculated by γ camera-based and thyroid uptake probe-based methods after administration of a diagnostic (131)I capsule in patients with benign thyroid disorders. METHODS The study group comprised 66 patients, of whom 26 were male (28-67 y old) and 40 female (20-65 y old). These patients had ben...

متن کامل

The Use of Gamma Probe in Thyroid Uptake Studies

Evaluation of thyroid uptake, by administration of small activities of radioactive iodine (I or I), is a well-defined procedure. Nowadays, nuclear medicine departments are using scintillation cameras coupled to pinhole collimators to perform such studies. On the other hand, gamma probes, which are normally used in radioguided surgical procedures, can technically be used for measuring the thyroi...

متن کامل

Measurement of iodine-123 thyroid uptake using a gamma camera with LEAP collimator.

OBJECTIVE This study compared the 123I thyroid uptake measurements obtained from a gamma camera fitted with a low-energy all-purpose (LEAP) collimator to those obtained from a thyroid uptake probe and gamma camera fitted with a pinhole (PH) collimator. METHODS Thirty-one patients (27 female and 4 male patients) were studied for comparison between a probe and a gamma camera fitted with LEAP co...

متن کامل

Estimating Tumor/Non-Tumor Uptake from Radiolabeled Monoclonal Antibodies using Scintigraphic Images and Dissecting the Animal Models

Introduction: Biodistribution study in animal models bearing tumors is one of the most important procedures in evaluation of fractional uptake of radiopharmaceuticals in the tumor and non-tumor organs. The aim of this study was to develop a new software-based method to determine activities that accumulate in the main organs as well as the tumor based on scintigraphy images, thereby obviating th...

متن کامل

A camera based calculation of 99mTc-MAG3 clearance using conjugate views method [Persian]

Background: Measurement of absolute or differential renal function using radiotracers plays an important role in the clinical management of various renal diseases. Gamma camera quantitative methods in approximation of renal clearance may potentially be as accurate as plasma clearance methods. However some critical factors such as kidney depth and background counts are still troublesome in...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014